The Oxford-Astra Zeneca vaccine: a viral vector-based vaccine

Three different vaccines have been authorised for emergency use in the United Kingdom to control the pandemic: two of them are mRNA vaccines, and one is based on a viral vector. The latter, called AZD1222, has been developed by Oxford University in collaboration with the biopharma company Astra Zeneca. AZD1222  is based in a chimpanzeeContinue reading “The Oxford-Astra Zeneca vaccine: a viral vector-based vaccine”

When viruses are the ally: successful gene therapy for retinal dystrophy and beta-thalassemia

The goal of gene therapy is to cure monofactorial genetic disorders, caused by mutations in a single gene. In the sequence of each gene are the instructions for the production of a protein, and every block of three bases (codon) corresponds to a specific amino acid. Alterations in the DNA sequence (mutations) affect the sequenceContinue reading “When viruses are the ally: successful gene therapy for retinal dystrophy and beta-thalassemia”

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